Advancing Oral Health Through Clinical & Translational Science
The Rutgers School of Dental Medicine Clinical Research Center (CRC) brings together NIH-funded scientists, clinician–investigators, industry partners and community health researchers to reimagine how oral health discoveries move from bench to bedside to the community.
RSDM’s CRC has transformed into a premier hub for Clinical & Translational Oral Health Research, spanning T0–T4 Translational science—from foundational biological discovery, to innovative biomaterial and host-microbial immunology studies, to human clinical trials, and finally population-level impact. This establishes RSDM CRC as one of the only U.S. dental schools with continuous capability across the entire translational spectrum.
T0: Foundational & Mechanistic Science
Cutting-edge faculty studying:
- Periodontal and peri-implant inflammation
- Biomaterial–host interactions
- Immunology of oral diseases
- Human multiomics & single-cell analytics
- Implant surface/titanium corrosion biology
- In vitro organoid & tissue-chip platforms
Supported by the infrastructure and scientific power of Rutgers’ institutional commitment to translational science:
-Rutgers Biomedical Health Sciences (RBHS)
-Rutgers Institute for Translational Medicine & Science (ITMS)
T1–T2: Proof-of-Concept & Preclinical to Clinical Pipeline
Our investigators translate basic discoveries into real-world prototypes through:
- Large-animal peri-implantitis models
- Biomaterial testing and surface engineering
- Human-centered ex vivo tissue models
- First-in-human early-phase clinical trials
- Patient-derived cellular assays
CRC infrastructure enables rapid movement from mechanism → intervention → clinical testing.
T3–T4: Community Health & Real-World Impact
This program focuses on:
- Community-level oral health outcomes
- Epidemiology of dental disease, disparities, and access
- Implementation research
- Pragmatic clinical trials
- Public health interventions targeting New Jersey communities
Our mission is simple: turn breakthrough ideas into real-world solutions that improve oral and systemic health.